Research Progress in C-S Bond Formation Reaction of Olefins with Organic Sulfur Reagents under Photocatalyst-Free and Non-Electrochemical Conditions

作者：Wang, Bowen; Zhou, Yongjun^*; Luo, Shihe; Luo, Xiaoyan; Chen, Weiqing; Yang, Shimin; Wang, Zhaoyang^*

来源：CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 41(1): 171-184.

DOI：10.6023/cjoc202006064

• alkene
• C-S bond formation reaction
• thiol
• sodium sulfinate
• aryl ethylene
• thioetherification
• difunctionalization

Olefin is an important synthetic synthon, and its concise and efficient transformation has been a research hotspot in the field of organic synthesis. In recent years, the C-S bond formation based on the olefin skeleton has received particular attention from scientists. Alkenes can react with common organic sulfur-containing reagents, including thiol, disulfide, sulfoxide, sulfonyl hydrazide, sulfonyl chloride, sodium sulfinate and other kinds of organosulfur reagents to build C-S bonds at the alpha-position or beta-position of olefin to synthesize sulfide, sulfoxide or sulfone. Thus, according to the different classification of the used organosulfur reagents, the recent research progresses in C-S bond formation reaction of olefins with organic sulfur reagents under photocatalyst-free conditions and non-electrochemical method is summarized. In the future, among the researches on the C-S bond formation reactions of olefins with inexpensive organosulfur reagents, asymmetrical synthesis and various difunctionalizations are still promising directions.