Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair

Authors：Yuka Nakazawa; Yuichiro Hara; Yasuyoshi Oka; Okiru Komine; Diana van den Heuvel; Chaowan Guo; Yasukazu Daigaku; Mayu Isono; Yuxi He; Mayuko Shimada; Kana Kato; Nan Jia; Satoru Hashimoto; Yuko Kotani; Yuka Miyoshi; Miyako Tanaka; Akira Sobue; Norisato Mitsutake; Tomoo Ogi

Source：Cell, 2020.

DOI：10.1016/j.cell.2020.02.010

• ▪RNA polymerase II
• RNAPII
• ubiquitination of RNAPII
• transcription coupled repair
• TCR
• nucleotide excision repair
• NER
• Cockayne syndrome
• CS
• UV-sensitive syndrome
• UVsS
• ChIP-seq
• UVSSA
• CRL/CSA/CSB
• TFIIH

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• Institution
  Leiden University Medical Center; Nagoya University Graduate School of Medicine; university of tokyo