A New Tirucallane Triterpenoid from Galla chinensis

作者:Li, Yuting; Tong, Xueli; Tian, Liwen*
来源:CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 41(6): 2511-2514.
DOI:10.6023/cjoc202012045

摘要

A new tirucallane triterpenoid was isolated from the ethyl acetate extract of Galla chinensis, along with five known tirucallane triterpenoids. Their structures were elucidated by extensive spectrosopic data analysis. It is the first time to report triterpenoids from G. chinensis. Masticadienonic acid (3), isomasticadienonic acid (4) and masticadienolic acid (5) showed neuroprotective activity at a concentration of 1.6 mu mol.L-1. This study provides a structure template for neuroprotection agent discovery.

  • 单位
    南方医科大学

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