[NN]-Chelate nickel complexes with Schiff base ligands: Synthesis, structure and catalytic activity in green amidation reaction

Authors：Guo, Wen; Liu, Zhen-Jiang; Wu, Fanhong; Luo, Yu-Zhou^*; Yao, Zi-Jian^*

Source：Applied Organometallic Chemistry, 2022, 36(9): e6808.

DOI：10.1002/aoc.6808

• amidation
• catalysis
• nickel complex
• Schiff base
• X-ray analysis

A series of N,N-coordinate nickel (II) complexes with Schiff base ligands have been synthesized. All N,N-coordinate nickel (II) complexes 1-4 were well characterized by IR and elemental analysis. Molecular structure of complex 1 was further characterized by single crystal X-ray diffraction analysis. All air and moisture stable nickel complexes showed efficient catalytic activity for the amidation reaction of a widely range of amides and primary alcohols. N-alkylated amides were given in good to excellent yields with liberating water as the sole byproduct. A variety types of functional groups tolerated well in such reaction condition. In addition, control experiments were carried out to understand this Ni-catalysis protocol.

• Institution
  Guilin University Of Technology; Chinese Academy of Science; shanghai institute of technology