Recent Developments in the use of Fluorine NMR in Synthesis and Characterisation

Authors：Peter W.A. Howe

Source：PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY, 2020.

DOI：10.1016/j.pnmrs.2020.02.002

• NMR
• 19F
• Review
• Applications

A review of developments in fluorine NMR of relevance to synthesis, characterisation and industrial applications of small organic molecules. Developments considered include those in spectrometer technology, computational methods and pulse sequences. The review of 79 references outlines applications in areas of identification, quantitation, mixture analysis, reaction monitoring, environmental studies and fragment-based drug design.
Graphical abstract

Download : Download high-res image (91KB)Download : Download full-size image