Isolation of infectious SARS-CoV-2 from urine of a COVID-19 patient

作者：Sun, Jing; Zhu, Airu; Li, Heying; Zheng, Kui; Zhuang, Zhen; Chen, Zhao; Shi, Yongxia; Zhang, Zhaoyong; Chen, Si-bei; Liu, Xuesong; Dai, Jun; Li, Xiaobo; Huang, Shuxiang; Huang, Xiaofang; Luo, Ling; Wen, Liyan; Zhuo, Jianfen; Li, Yuming; Wang, Yanqun; Zhang, Lu; Zhang, Yanjun; Li, Fang; Feng, Liqiang; Chen, Xinwen; Zhong, Nanshan; Yang, Zifeng^*; Huang, Jicheng^*; Zhao, Jincun^*; Li, Yi-min

来源：Emerging Microbes & Infections, 2020, 9(1): 991-993.

DOI：10.1080/22221751.2020.1760144

• COVID-19
• urine
• transmission
• SARS-CoV-2
• virus isolation

SARS-CoV-2 caused a major outbreak of severe pneumonia (COVID-19) in humans. Viral RNA was detected in multiple organs in COVID-19 patients. However, infectious SARS-CoV-2 was only isolated from respiratory specimens. Here, infectious SARS-CoV-2 was successfully isolated from urine of a COVID-19 patient. The virus isolated could infect new susceptible cells and was recognized by its' own patient sera. Appropriate precautions should be taken to avoid transmission from urine.

• 单位
  1; 中国科学院; 广州医学院