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Advances in Treatment Models of Advanced Gastric Cancer

Li, Tao; He, Yufang; Zhong, Qinglei; Yu, Jiang; Chen, Xinhua*
Science Citation Index Expanded
南方医科大学; 1

摘要

The prognosis of advanced gastric cancer (AGC) is extremely poor, and the therapeutic effect of traditional palliative chemotherapy is far from satisfactory. To overcome this bottleneck, palliative surgery resection, perioperative chemotherapy combined with surgical resection, hyperthermic intraperitoneal chemotherapy (HIPEC), pressurized intraperitoneal aerosol chemotherapy (PIPAC), radiation therapy, molecular-targeted therapy have been explored in AGC. Although considerable progress has been achieved, there is still no overwhelming therapeutic method. Due to the high heterogeneity of AGC, it is particularly vital to reshaped the paradigm of gastric cancer therapy according to the characteristics of clinical classifications and molecular subtypes.

关键词

gastric cancer cancer treatment chemotherapy HIPEC conversion therapy molecular-targeted therapy