Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China

作者：Aiping Wu; Yousong Peng; Baoying Huang; Xiao Ding; Xianyue Wang; Peihua Niu; Jing Meng; Zhaozhong Zhu; Zheng Zhang; Jiangyuan Wang; Jie Sheng; Lijun Quan; Zanxian Xia; Wenjie Tan; Genhong Cheng; Taijiao Jiang

来源：Cell Host and Microbe, 2020, 27(3): 325-328.

DOI：10.1016/j.chom.2020.02.001

An in-depth annotation of the newly discovered coronavirus (2019-nCoV) genome has revealed differences between 2019-nCoV and severe acute respiratory syndrome (SARS) or SARS-like coronaviruses. A systematic comparison identified 380 amino acid substitutions between these coronaviruses, which may have caused functional and pathogenic divergence of 2019-nCoV.

• 单位
  中国医学科学院; 中国疾病预防控制中心