A novel AuNP colorimetric sensor based on a polyadenine probe for ultra-sensitive detection of Ag+

作者：Li, Dandan; Wen, Qilin; Zhou, Yanyu; Huang, Guidan; Xi, Huai; Zhang, Lianming; Li, Ziyuan; Zhu, Wenyuan^*

来源：Analytical Methods, 2023, 15(5): 626-630.

DOI：10.1039/d2ay02026b

• ABSORPTION SPECTROMETRIC DETERMINATION
• SILVER-ION
• GOLD NANOPARTICLES
• PRECONCENTRATION
• METALS

Silver(i) ions (Ag+) are harmful to humans and can be bioaccumulated in organisms. Although numerous methods for Ag+ analysis have been established, new strategies are still in urgent need. Here, we propose a colorimetric sensor based on polyadenine (polyA)-mediated DNA-functionalized gold nanoparticles (AuNPs) for the specific measurement of Ag+ ions. In this strategy, a polyA-modified Au probe with high uniformity was assembled successfully. The method was based on Ag+-induced aggregation of the probe. Ag+ was reflected according to the color variations of solution. Taking advantage of the low cost and convenient assembly of the polyA-based Au probe, our strategy determined Ag+ with high sensitivity and wide range. In addition, by changing probes or nanoparticles, the proposed strategy is expected to be a universal platform for detecting other analytes in environmental and even biological samples.

• 单位
  桂林理工大学