Ruthenium complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers

作者：Li Linlin; Wong Yum Shing; Chen Tianfeng^*; Fan Cundong; Zheng Wenjie

来源：Dalton Transactions, 2012, 41(4): 1138-1141.

DOI：10.1039/c1dt11950h

A series of ruthenium complexes containing bis-benzimidazole derivatives have been synthesized and identified as able to target mitochondria and induce caspase-dependent apoptosis in cancer cells through superoxide overproduction.

• 单位
  暨南大学; 香港大学; 济南大学