A new benzofuran glycoside from the fruit ofClausena lansium

作者：Ao, Huiting; Jia, Xuchao; Dong, Lihong; Zhang, Ruifen; Liu, Lei; Huang, Fei; Wang, Lixia^*; Zhang, Mingwei^*

来源：NATURAL PRODUCT RESEARCH, 2022, 36(2): 501-507.

DOI：10.1080/14786419.2020.1788557

• Clausena lansium(Lour
• ) Skeels
• wampee
• benzofuran glycoside
• phenolics
• antioxidant activity
• amylase inhibition

In this work, we isolated a new benzofuran glycoside, 6-beta-d-glucosyl-6,7-dihydroxy-5-benzofuranpropanoic acid methyl ester (1), together with six known compounds (2-7) from the fruits ofClausena lansium(Lour.) Skeels. Extensive spectroscopic methods were employed to elucidate their structures. Herein, compounds2,3,5and6were reported fromClausena lansium(Lour.) Skeels for the first time. Moreover, compounds1,2,4and6showed comparable 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) radical scavenging activity tol-ascorbic acid, and compound4also exhibited potent 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and ferric reducing antioxidant power (FRAP). All of the compounds showed oxygen radical absorbance capacity (ORAC) values ranging from 0.3 to 3.6 mu mol trolex equivalent/mu mol. In addition, compounds3and5also demonstrated good alpha-amylase inhibitory activity.

• 单位
  广东省农业科学院