Genetic effects of an air discharge plasma on Staphylococcus aureus at the gene transcription level

作者:Xu Zimu; Wei Jun; Shen Jie; Liu Yuan; Ma Ronghua; Zhang Zelong; Qian Shulou; Ma Jie; Lan Yan; Zhang Hao; Zhao Ying; Xia Weidong*; Sun Qiang; Cheng Cheng; Chu Paul K
来源:Applied Physics Letters, 2015, 106(21): 213701.
DOI:10.1063/1.4921754

摘要

The dynamics of gene expression regulation (at transcription level) in Staphylococcus aureus after different doses of atmospheric-pressure room-temperature air plasma treatments are investigated by monitoring the quantitative real-time polymerase chain reaction. The plasma treatment influences the transcription of genes which are associated with several important bio-molecular processes related to the environmental stress resistance of the bacteria, including oxidative stress response, biofilm formation, antibiotics resistance, and DNA damage protection/repair. The reactive species generated by the plasma discharge in the gas phase and/or induced in the liquid phase may account for these gene expression changes.

  • 单位
    香港城市大学; 中国科学院合肥物质科学研究院