Recent progress in the applications of amino-yne click chemistry

作者：Zhang, Jie; Zhang, Zhiming; Wang, Jia; Zang, Qiguang; Sun, Jing Zhi^*; Tang, Ben Zhong^*

来源：Polymer Chemistry, 2021, 12(20): 2978-2986.

DOI：10.1039/d1py00113b

Click chemistry has been rapidly developed in recent years. Among various established click reaction systems, the spontaneous amino-yne click reaction stands out. In addition to the general advantages associated with click reactions, amino-yne click reaction possesses extra merits, such as spontaneity of reactions, ubiquity of amines and cleavability of products with specific stimuli. Therefore, the amino-yne click reaction has become a useful tool and provided convenience for scientists in various fields since its first report in 2017. In this review, we capture the recent progress in the applications of amino-yne click reaction, which are briefly classified and reviewed in the fields of surface immobilization, drug delivery carrier design, hydrogel materials preparation and synthesis of polymers with unique structures.

• 单位
  浙江大学