Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia

Alshukairi, Abeer N.^*; Zhao, Jincun; Al-Mozaini, Maha A.; Wang, Yanqun; Dada, Ashraf; Baharoon, Salim A.; Alfaraj, Sara; Ahmed, Waleed A.; Enani, Mushira A.; Elzein, Fatehi E.; Eltayeb, Nazik; Layqah, Laila; El-Saed, Aiman; Bahaudden, Husam A.; Haseeb, Abdul; El-Kafrawy, Sherif A.; Hassan, Ahmed M.; Siddiq, Najlaa A.; Alsharif, Ibtihaj; Qushmaq, Isamel; Azhar, Esam, I; Perlman, Stanley; Memish, Ziad A.

Science Citation Index Expanded

广州医学院; 1

摘要

Understanding the immune response to Middle East respiratory syndrome coronavirus (MERS-CoV) is crucial for disease prevention and vaccine development. We studied the antibody responses in 48 human MERS-CoV infection survivors who had variable disease severity in Saudi Arabia. MERS-CoV specific neutralizing antibodies were detected for 6 years postinfection.

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