A dual-mode sensor based on colorimetric and Tyndall effect of gold nanoparticles for ultra-sensitive detection of Hg2+

作者：Li, Dandan; Wen, Qilin; Zhou, Yanyu; Li, Dan; Xi, Huai; Huang, Guidan; Liang, Jinhua; Xiao, Xiaofen; Zhu, Wenyuan^*

来源：Analytical Sciences, 2023, 39(4): 565-571.

DOI：10.1007/s44211-023-00273-0

• Dual mode
• Hg2+
• Colorimetric
• Tyndall effect
• Gold nanoparticles

Mercury ion (Hg2+) is the most widespread and highly toxic environmental pollutant, which exerts numerous adverse effects on environmental and human health. There is an urgent need to develop a convenient method for detecting Hg2+. Herein, a novel dual-mode sensor based on colorimetric and Tyndall effect of gold nanoparticles was developed for ultra-sensitive determination of Hg2+. In this strategy, a polyA-modified Au probe with high uniformity was assembled successfully. Both modes were based on Hg2+-induced aggregation of the probes. Hg2+ was reflected according to the color variations of solution and the Tyndall effect of Au reporter. With the aid of a laser pointer, the Tyndall mode demonstrated about 615-fold improvement on sensitivity compared with the colorimetry way. Taking advantages of low cost and convenient assembly of polyA-based Au probe and the combination of colorimetry and Tyndall effect, our strategy determined the Hg2+ with high sensitivity and wide range. By changing probes or nanoparticles, the proposed strategy is expected to be a universal platform for detecting other analytes in environmental and even biological samples.

• 单位
  桂林理工大学