Novel cationic meso-CF3 BODIPY-based AIE fluorescent rotors for imaging viscosity in mitochondria

作者：Shi, Wen-Jing^*; Yang, Jinrong; Wei, Yong-Feng; Li, Xiao-Tong; Yan, Xu-Hui; Wang, Yuxuan; Leng, Huaxiang; Zheng, Liyao; Yan, Jin-wu^*

来源：Chemical Communications, 2022, 58(12): 1930-1933.

DOI：10.1039/d1cc06532g

• LYSOSOMAL VISCOSITY
• PROBE
• MOTION

Two novel meso-CF3 BODIPY-based fluorescent rotors have been rationally prepared and found to sensitively respond to viscosity in living cells with a fluorescence "turn-on" effect, attributed to the special restricted rotation of meso-CF3 group in viscous environments. Interestingly, a monostyryl probe with one cationic group exhibits good mitochondrial localization and AIE property.

• 单位
  广州大学