Cobalt-Catalyzed Protodeboronation of Aryl and Vinyl Boronates

Authors：Li, Ninglin; Xiong, Fuqiang; Gao, Ke^*

Source：Journal of Organic Chemistry, 2021, 86(2): 1972-1979.

DOI：10.1021/acs.joc.0c02570

• METAL-FREE PROTODEBORONATION
• BORONIC ACIDS
• ARYLBORONIC ACIDS
• PALLADIUM NANOPARTICLES
• SELECTIVE DEUTERATION
• COUPLING REACTIONS
• DEUTERIUM
• ALKENES
• BOND
• FUNCTIONALIZATION

An efficient cobalt-based catalytic system for protodeboronation of various aryl and vinyl boronates is described. The reaction is capable of tolerating a wide range of functional groups. The reaction is also extended to deuterodeboronation with D2O, which provides a potential protocol for the synthesis of regiospecifically deuterated arenes and olefins.