Biomedical polymers: synthesis, properties, and applications

作者：Chen, Wei-Hai; Chen, Qi-Wen; Chen, Qian; Cui, Chunyan; Duan, Shun; Kang, Yongyuan; Liu, Yang; Liu, Yun; Muhammad, Wali; Shao, Shiqun; Tang, Chengqiang; Wang, Jinqiang; Wang, Lei; Xiong, Meng-Hua; Yin, Lichen; Zhang, Kuo; Zhang, Zhanzhan; Zhen, Xu; Feng, Jun; Gao, Changyou; Gu, Zhen; He, Chaoliang; Ji, Jian; Jiang, Xiqun; Liu, Wenguang; Liu, Zhuang; Peng, Huisheng; Shen, Youqing; Shi, Linqi; Sun, Xuemei; Wang, Hao; Wang, Jun; Xiao, Haihua; Xu, Fu-Jian; Zhong, Zhiyuan; Zhang, Xian-Zheng

来源：Science China Chemistry, 2022, 65(6): 1010-1075.

DOI：10.1007/s11426-022-1243-5

• biomedical polymer
• nanomedicine
• cancer therapy
• drug delivery
• bioimaging and biosensing
• tissue engineering
• regenerative medicine
• cytotoxicity
• biocompatibility

Biomedical polymers have been extensively developed for promising applications in a lot of biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis, biosensing, regenerative medicine, and disease treatment. In this review, we summarize the most recent advances in the synthesis and application of biomedical polymers, and discuss the comprehensive understanding of their property-function relationship for corresponding biomedical applications. In particular, a few burgeoning bioactive polymers, such as peptide/biomembrane/microorganism/cell-based biomedical polymers, are also introduced and highlighted as the emerging biomaterials for cancer precision therapy. Furthermore, the foreseeable challenges and outlook of the development of more efficient, healthier and safer biomedical polymers are discussed. We wish this systemic and comprehensive review on highlighting frontier progress of biomedical polymers could inspire and promote new breakthrough in fundamental research and clinical translation.

• 单位
  北京化工大学; 苏州大学; 国家纳米科学中心; 中国科学院; 南开大学; 复旦大学; 浙江大学; 天津大学; 南京大学; 武汉大学