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Biomedical polymers: synthesis, properties, and applications

Chen, Wei-Hai; Chen, Qi-Wen; Chen, Qian; Cui, Chunyan; Duan, Shun; Kang, Yongyuan; Liu, Yang; Liu, Yun; Muhammad, Wali; Shao, Shiqun; Tang, Chengqiang; Wang, Jinqiang; Wang, Lei; Xiong, Meng-Hua; Yin, Lichen; Zhang, Kuo; Zhang, Zhanzhan; Zhen, Xu; Feng, Jun; Gao, Changyou; Gu, Zhen; He, Chaoliang; Ji, Jian; Jiang, Xiqun; Liu, Wenguang; Liu, Zhuang; Peng, Huisheng; Shen, Youqing; Shi, Linqi; Sun, Xuemei; Wang, Hao; Wang, Jun; Xiao, Haihua; Xu, Fu-Jian; Zhong, Zhiyuan; Zhang, Xian-Zheng
Science Citation Index Expanded
复旦大学; 国家纳米科学中心; 北京化工大学; 南京大学; 南开大学; 浙江大学; 苏州大学; 天津大学; 武汉大学; 中国科学院

摘要

Biomedical polymers have been extensively developed for promising applications in a lot of biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis, biosensing, regenerative medicine, and disease treatment. In this review, we summarize the most recent advances in the synthesis and application of biomedical polymers, and discuss the comprehensive understanding of their property-function relationship for corresponding biomedical applications. In particular, a few burgeoning bioactive polymers, such as peptide/biomembrane/microorganism/cell-based biomedical polymers, are also introduced and highlighted as the emerging biomaterials for cancer precision therapy. Furthermore, the foreseeable challenges and outlook of the development of more efficient, healthier and safer biomedical polymers are discussed. We wish this systemic and comprehensive review on highlighting frontier progress of biomedical polymers could inspire and promote new breakthrough in fundamental research and clinical translation.

关键词

biomedical polymer nanomedicine cancer therapy drug delivery bioimaging and biosensing tissue engineering regenerative medicine cytotoxicity biocompatibility