NIR luminogen for low-temperature photothermal therapy by triggering HSP90α down-regulation

作者：Yang, Xinzhe; Ding, Keke; Zhang, Guiquan; Han, Pengbo; Hu, Rong^*; Wang, Zhiming; Qin, Anjun^*; Tang, Ben Zhong^*

来源：Chemical Communications, 2023, 59(19): 2743-2746.

DOI：10.1039/d2cc06932f

A near-infrared (NIR) luminogen TST was designed and used to efficiently trigger HSP90 alpha protein knockdown through photo-thermal conversion based on a gene interference strategy, by which in vitro and in vivo tumor ablation were significantly acquired at low-temperature.

• 单位
  苏州大学; 1