TT Virus in Peripheral Blood Cells From Patients with Human Papillomavirus (HPV): Investigating Association with Cervical Carcinoma

作者：Suzuki Patricia Sayuri; de Oliveira Karen Brajao^*; do Amaral Herrera Ana Cristina; Borelli Sueli Donizete; Guembarovski Roberta Losi; Coral de Oliveira Carlos Eduardo; Oda Julie Massayo Maeda; Murobushi Ozawa Patricia Midori; Ehara Watanabe Maria Angelica

来源：Brazilian Archives of Biology and Technology, 2014, 57(2): 228-232.

• TTV DNA
• HPV
• cervical cancer

Torque Teno Virus (TTV) presence was investigated in peripheral blood of 117 brazilian women by nested polymerase chain reaction. TTV DNA was observed in 18.6% of healthy donors and in 24.32% Human Papillomavirus (HPV) patients. TTV presence was also investigated in the HPV positive group for comparison between the cervical cancer and noncancerous patients. TTV DNA prevalence was significantly higher among the HPV positive patients with cervical cancer (57.14%) than in HPV noncancerous patients (16.67%). Thus, the presence of TTV infection could be a risk factor for cancer development in the patients presenting HPV-TTV coinfection. Further studies are required to clarify the TTV influence in HPV pathogenesis.