科研之友
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摘要
Objective To explore the clinical effect of protein-free calf blood extract eye gel and sodium hy-aluronate eye drops in the prevention and treatment of dry eye after laser-assisted in situ keratomileusis (LASIK). Methods One hundred and sixty patients (320 eyes) undergoing LASIK in our hospital from June 2011 to June 2014 were selected and then divided them into group A and group B, with 80 patients (160 eyes) in each group. Patients in group A were treated with protein-free calf blood extract eye gel, while patients in the group B were treated with sodi-um hyaluronate eye drops. Before treatment and after 4 weeks of treatment, subjective dry eye symptom scores, tear break-up time (BUT), SchirmerⅠtest and corneal fluorescein staining were observed and compared to evaluate the clinical effect of the two groups. Results After 4 weeks of treatment, the total effective rate in group A was 91.25%, significantly higher than 73.75%in group B (P <0.05). There was no significant difference in SchirmerⅠtest between the two groups after treatment (P> 0.05), but the subjective dry eye symptom scores of group A was sig-nificantly lower, with the BUT significantly longer and the score of corneal fluorescein staining significantly lower (P <0.05). Conclusion In the prevention and treatment of dry eye after LASIK, the clinical effect of protein-free calf blood extract eye gel is better than sodium hyaluronate eye drops, which is worthy of further clinical application.
