Evidence-based guideline for the prevention and management of perioperative infection

作者：Wang, Qiaoyu; Cao, Mingnan; Tao, Hua; Fei, Zhimin; Huang, Xiufeng; Liang, Pixia; Liu, Baiyun; Liu, Jianping; Lu, Xiaoyang; Ma, Penglin; Si, Shuyi; Wang, Shuo; Zhang, Yuewei; Zheng, Yingli; Zang, Lei; Chen, Xiao; Dong, Zhanjun; Ge, Weihong; Guo, Wei; Hu, Xin; Huang, Xin; Li, Ling; Liang, Jianshu; Liu, Baoge; Liu, Dong; Liu, Linna; Liu, Songqing; Liu, Xianghong; Miao, Liyan; Ren, Haixia; Shi, Guangzhi; Shi, Luwen; Sun, Shumei; Tao, Xia; Tong, Rongsheng; Wang, Cheng; Wang, Bin; Wang, Jincheng

来源：Journal of Evidence-Based Medicine, 2023, 16(1): 50-67.

DOI：10.1111/jebm.12514

• antimicrobials
• Delphi
• GRADE
• guideline
• perioperative infection

BackgroundWe have updated the guideline for preventing and managing perioperative infection in China, given the global issues with antimicrobial resistance and the need to optimize antimicrobial usage and improve hospital infection control levels. MethodsWe conducted a comprehensive evaluation of the evidence for prevention and management of perioperative infection, based on the concepts of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. The strength of recommendations was graded and voted using the Delphi method and the nominal group technique. Revisions were made to the guidelines in response to feedback from the experts. ResultsThere were 17 questions prepared, for which 37 recommendations were made. According to the GRADE system, we evaluated the body of evidence for each clinical question. Based on the meta-analysis results, recommendations were graded using the Delphi method to generate useful information. ConclusionsThis guideline provides evidence to perioperative antimicrobial prophylaxis that increased the rational use of prophylactic antimicrobial use, with substantial improvement in the risk-benefit trade-off.

• 单位
  南京大学; 苏州大学; 1; 中国医学科学院; 北京大学; 南方医科大学; 河北医科大学; 山东大学; 上海交通大学; 中山大学; 四川大学; 华中科技大学; 中国人民解放军第四军医大学; 吉林大学; 复旦大学; 浙江大学