Association of blood glucose level and prognosis of inpatients with coexistent diabetes and COVID-19

作者：Duan, Weiwei; Li, Liangyu; Li, Xuesong; Zhu, Mengyan; Wu, Lingxiang; Wu, Wei; Li, Kening; Liang, Yuan; Ding, Rong; You, Wenhua; Wang, Ziyu; Huang, Bin; Wu, Min; Zhang, Tingting; Li, Jie; Li, Yan; Shao, Jiaofang; Lin, Changsong; Li, Pengping; Wang, Qianghu; Wang, Shukui; Xia, Xinyi; Liu, Yu; Lyu, Sali

来源：ENDOCRINE, 2022, 75(1): 1-9.

DOI：10.1007/s12020-021-02923-7

• COVID-19
• Type 2 diabetes
• Glucose control
• Prognosis analysis

Type 2 diabetes (T2D) increases the risk of coronavirus disease (COVID-19). This study investigates the association between glucose control of COVID-19 patients with T2D in first 7 days after hospital admission and prognosis. A total of 252 infected inpatients with T2D in China were included. Well-controlled blood glucose was defined as stable fasting blood glucose (FBG) levels in the range of 3.9-7.8 mmol/L during first 7 days using indicators of average (FBG(A)), maximum (FBG(M)) or first-time (FBG(1)) FBG levels. The primary endpoint was admission to intensive care unit or death. Hazard ratio (HR) of poorly controlled glucose level group compared with well-controlled group were 4.96 (P = 0.021) for FBG(M) and 5.55 (P = 0.014) for FBG(A). Well-controlled blood glucose levels in first 7 days could improve the prognosis of COVID-19 inpatients with diabetes.

• 单位
  y; 南京大学; 1; 南方医科大学