Copper-Mediated Addition Reactions to Styrenes with1,1,1-Trifluoro-2,2-dichloroethane or1,1,1-Trifluoro-2,2,2-tricholorethane

Source：有机化学, 2017, 37(7).

DOI：10.6023/cjoc201702037

• HCFC
• copper
• radical
• alkene

An efficient CuCl/bpy-mediated atom transfer radical addition reaction of styrenes with CF3CHC12 and CF3CC13 is developed.Bpy which was added to enhance the reducibility of copper was crucial for activating one inert C-C1 bond of CF3CHC12 and CF3CC13 to form single radical adducts.

• Institution
  中国科学院上海有机化学研究所