Microfluidic system for particle manipulation based on swirl

作者:Ou, Zhiming; Zhang, Qin*; Hu, Shuai; Dang, Yanping
来源:Applied Physics Letters, 2023, 123(1): 013508.
DOI:10.1063/5.0158042

摘要

This paper proposes a microfluidic system for particle manipulation, which is comprised of a microfluidic chip, a driving device, a manipulation dish, and associated accessories. The microfluidic chip integrates a swirl structure with three microchannels, allowing for trapping, rotating, transporting, pairing, and enriching particles with different parameters by controlling the jet velocity of each microchannel. The driving device is mainly constructed with three push-pull syringe pumps to ensure the stability of the swirl flow field during manipulation. Experimental results demonstrate that the developed microfluidic system can achieve multifunctional and long-term (hours) particle manipulation.