科研之友
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摘要
A novel noble transition metal- and external oxidant-free electrochemical cyclization/aromatization of aniline-tethered alkylidenecyclopropanes enabled by N-H/C-H functionalization is described. Various highly functionalized benzo[c]carbazoles were constructed in atom-economical and sustainable manners, and exhibited a broad substrate scope and excellent regioselectivity. In addition, H-2 was the only theoretical byproduct in this protocol. Mechanistic studies indicated that the reaction proceeded through nitrogen-centered radical generation, cleavage of C-C bonds, C(sp(2))-H functionalization and aromatization cascades.
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单位兰州大学; y; 南昌航空大学
