Amine-Directed Regioselective Pyridyl Csp2-H Aminovinylation

作者：Luo, Zhongfeng; Wang, Chengjie; Jiang, Huanfeng; Zeng, Wei^*

来源：Organic Letters, 2023, 25(38): 7020-7024.

DOI：10.1021/acs.orglett.3c02602

• DIRECT ARYLATION
• FUNCTIONALIZATION
• ANNULATION
• PYRIDINES
• CYCLOADDITION
• ALKYNES

A Rh-catalyzed amine-directed cross-coupling of 2-aminopyridines with 1-sulfonyl-triazoles has been developed. The method provides an efficient approach to access 5-aminovinylpyridines with wide functional group tolerance.