Fast protodeboronation of arylboronic acids and esters with AlCl3 at room temperature

作者：Yuan, Zhijun; Liang, Yunshi; He, Yiting; Deng, Huiying; Wu, Haiting; Lin, Bohong; Zhang, Jing^*

来源：Australian Journal of Chemistry, 2023, 76(4): 194-200.

DOI：10.1071/CH23028

• B-11 NMR spectroscopy
• AlCl3
• arylboronic acids
• arylboronic esters
• Bronsted acid
• Lewis acid
• mild reaction condition
• protodeboronation

AlCl3-mediated protodeboronation of arylboronic acids and esters is reported herein. This method features mild reaction conditions, high reaction yields, as well as short reaction times. Mechanistic studies based on B-11 NMR spectroscopy suggest that it might proceed through initial boron activation by coordination of AlCl3 to the oxygen atom of arylboronic acid or ester groups.

• 单位
  1; 广州中医药大学