Three new phenanthrenes from Pholidota chinensis Lindl. and their antibacterial activity

作者:Ti, Huihui*; Zhuang, Zixi; Li, Yan; Wei, Guozhu; Wang, Fei*
来源:NATURAL PRODUCT RESEARCH, 2022, 36(8): 2056-2062.
DOI:10.1080/14786419.2020.1845168

摘要

Three new phenanthrenes were isolated from Pholidota chinensis Lindl. Their structures were elucidated on the basis of spectroscopic techniques and comparison of their data to the values reported in the literature. From the 95% EtOH extract, three new compounds, namely 9, 10-dihydro-2, 4, 6-trihydroxy-7-methoxyphenanthrene (1), 11-methoxyflaccidin (2), and 2-methoxy-3,7-dihydroxy-5H phenanthro[4,5-bcd] pyran (3), were identified. Compound 3 showed an MIC50 of 68.39 mu M against Staphylococcus aureus subsp. Aureus.

  • 单位
    广东药学院