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Chemoproteomics-Enabled Discovery of a Potent and Selective Inhibitor of the DNA Repair Protein MGMT
Authors:Wang Chao; Abegg Daniel; Hoch Dominic G; Adibekian Alexander
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Source:
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
, 2016, 55(8).
DOI:10.1002/anie.201511301
Activity-based protein profiling
Cell viability assays
DNA methyltransferases
Drug discovery
MGMT
Pharmacological properties
Proteomics
Quantitative proteomics
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