科研之友
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摘要
One new nornemoralisin (1) and two new nemoralisin (2 and 3) diterpenoids, along with one known analogue (4), were isolated from the stems and leaves of Aphanamixis polystachya. Compound 1 represents the first example of an acyclic diterpenoid featuring a unique 18-nornemoralisin skeleton, and the structures of these new compounds were established mainly by NMR and MS methods. The antifungal activities of compounds 1-3 applied alone or in combination with fluconazole against drug-resistant Candida albicans were investigated.
