Hydration of terminal alkynes catalyzed by cobalt corrole complex

作者：Lai, Jia-Wei; Liu, Zhao-Yang; Chen, Xiao-Yan; Zhang, Hao; Liu, Hai-Yang^*

来源：2020, 61(43): 152426.

DOI：10.1016/j.tetlet.2020.152426

• Cobalt(III) corrole
• Hydration
• Terminal alkynes

Cobalt(III) corrole was firstly applied to the hydration of terminal alkynes. The alkyne hydration proceeded in good to excellent yield with 0.03 to 0.3 mol% cobalt corrole catalyst loading. A wide range of substrates were tolerated. Particularly, the reaction can give 90% yield in a gram scale experiment.