Mechanochemical Electrophilic Mono- or Disulfur Transfer: Construction of P(O)-S or P(O)-S-S Bonds

作者：Zhang, Ziwu; Lao, Tianfeng; Deng, Lichan; Zhang, Chen; Liu, Jubin; Fu, Min; Su, Zhengquan; Yu, Yue^*; Cao, Hua^*

来源：Organic Letters, 2022, 24(39): 7222-7226.

DOI：10.1021/acs.orglett.2c03018

• THIOPHOSPHATES
• PHOSPHONATES
• DIOXIDE

Under mechanochemically induced conditions, a wide range of diarylphosphine oxides or H-phosphonates react with trisulfide dioxides to afford various thiophosphate derivatives in good yields. Selective S-S bond cleavage of trisulfide dioxides determined by connecting groups is proposed as the key step in the construction of P(O)-S or P(O)-S-S bonds, which is supported by calculations.

• 单位
  广东药学院; y; 中山大学