Giant Hepatic Regenerative Nodule in a Patient With Hepatitis B Virus-related Cirrhosis

作者：Li, Long^*; Feng, Jie

来源：Journal of Clinical and Translational Hepatology, 2022, 10(4): 778-782.

DOI：10.14218/JCTH.2021.00266

• Regenerative nodules
• Cirrhosis
• Hepatitis B virus
• Computed tomography
• Magnetic resonance imaging

Hepatic regenerative nodules are reactive hepatocellular proliferations that develop in response to liver injury. Giant hepatic regenerative nodules of 10 cm or more are extremely rare and have only been reported in patients with biliary atresia or Alagille syndrome. A 50-year-old man presented with a pathologically confirmed giant 11.3x9.4x11.2 cm hepatic regenerative nodule and hepatitis B virus-related cirrhosis. Imaging of intrahepatic nodule included mild hyper-enhancement in the portal phase of contrast-enhanced CT and the hepatobiliary phase in the gadoxetic acid-enhanced MRI scan, as well as the portal vein crossing through sign in the setting of liver cirrhosis. This case highlights the imaging characteristics of giant hepatic regenerative nodules in hepatitis cirrhosis.

• 单位
  广州医学院; 南方医科大学