2-Pyrones from endophytic fungus Diaporthe foeniculina BZM-15

作者：Yu, Zhonghua; Lu, Xiuxiang; Choi, Jaehyuck; Deng, Shulin; Xiong, Binghong; Zhang, Wenge; Wang, Huan; Wang, Sasa^*; Tan, Haibo^*

来源：NATURAL PRODUCT RESEARCH, 2022, 36(19): 4853-4861.

DOI：10.1080/14786419.2021.1904400

• Diaporthe foeniculina
• foeniculins A-D
• 2-pyrones
• cytotoxic activity

Foeniculins A-C (1-3) together with a pair of enantiomers (+/-)-foeniculin D (4) were isolated from endophytic fungus Diaporthe foeniculina BZM-15. Their structures including absolute configurations were unambiguously established by extensive interpretation of the NMR and HR-ESI-MS data, ECD measurements powered by molecular calculations, as well as Mo-2(OAc)(4) mediated CD methodology. The cytotoxic activity assay disclosed that these compounds didn't show any noticeable cytotoxic activity.

• 单位
  中国科学院研究生院