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2-Pyrones from endophytic fungus Diaporthe foeniculina BZM-15

Yu, Zhonghua; Lu, Xiuxiang; Choi, Jaehyuck; Deng, Shulin; Xiong, Binghong; Zhang, Wenge; Wang, Huan; Wang, Sasa*; Tan, Haibo*
Science Citation Index Expanded
中国科学院研究生院; 中国科学院

摘要

Foeniculins A-C (1-3) together with a pair of enantiomers (+/-)-foeniculin D (4) were isolated from endophytic fungus Diaporthe foeniculina BZM-15. Their structures including absolute configurations were unambiguously established by extensive interpretation of the NMR and HR-ESI-MS data, ECD measurements powered by molecular calculations, as well as Mo-2(OAc)(4) mediated CD methodology. The cytotoxic activity assay disclosed that these compounds didn't show any noticeable cytotoxic activity.

关键词

Diaporthe foeniculina foeniculins A-D 2-pyrones cytotoxic activity