The Therapy-Related Symptom Checklist for Children as a Method for Monitoring Symptoms in Chinese Children With Cancer: Linguistic Validation and Cross-Cultural Adaptation

作者：Alelayan, Hasan; Wen, Huangliang; Li, Hui; Ge, Jing; Han, Wei; Liao, Xiaoyan^*

来源：Pain Management Nursing, 2022, 23(6): 855-860.

DOI：10.1016/j.pmn.2021.12.006

• PATIENT-REPORTED OUTCOMES
• QUALITY-OF-LIFE
• TRANSLATION
• VALIDITY
• SEVERITY

Background: Children with cancer commonly experience severe symptoms. These may be managed by routine monitoring of their occurrence and severity using a validated tool. Aim: This study aimed to trans-late and culturally validate a simplified Chinese version of the Therapy-Related Symptom Checklist for Children (TRSC-C). Design : Qualitative method. Participants and setting: We recruited children with cancer from a pediatric department of a tertiary hospital in Guangzhou, China. Methods: We used forward and backward translation by bilingual translators and standardized cognitive interviewing for linguistic validation and to check cross-cultural adaptation. A panel of experts assessed content validity. Results: Agreement was reached on cultural applicability, suitability for intended purpose, and clarification of the pre-test version. The content validity was good (indices ranged from 0.80-0.90). Fifteen Chinese children with cancer (aged 8-18 years) were included in cognitive interviews. The cognitive de-briefing showed that the instrument was easy to understand and appropriate for monitoring symptoms in children with cancer. Some words were adjusted following participants' comments. Conclusions: The simplified Chinese version of the TRSC-C was semantically and conceptually equivalent to the original version. Children between 8-18 years old can use this instrument to report symptoms and share their experiences about their disease and treatment.

• 单位
  南方医科大学