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Five new diarylheptanoids from the rhizomes of Curcuma kwangsiensis and their antiproliferative activity

Chen Shao Dan; Gao Jin Tao; Liu Jing Gong; Liu Bo; Zhao Rui Zhi; Lu Chuan Jian*
SCI
广东省人民医院; 广州中医药大学

摘要

Five new diarylheptanoids (1-5), along with nine known ones (6-14), were isolated from the rhizomes of Curcuma kwangsiensis. Their structures were established on the basis of spectroscopic analyses. Compounds 1-3 were cyclic diarylheptanoids rarely discovered from C. kwangsiensis. Of all the isolated compounds, compound 4 showed moderate antiproliferative activity on HH and HaCaT cells.

关键词

Curcuma kwangsiensis Diarylheptanoids Antiproliferation HH cells HaCaT cells