Cytospones E-J from the endophytic fungus Cytospora rhizophorae

作者：Zhang, Yanjiang; Liu, Hongxin; Chen, Yuchan; Wei, Shanshan; Zhang, Weimin^*; Tan, Haibo^*

来源：FITOTERAPIA, 2022, 163: 105324.

DOI：10.1016/j.fitote.2022.105324

• Cytospora rhizophorae
• Endophytic fungus
• Gynochthodes officinalis
• Anti-inflammatory activity
• ? -Glucosidase inhibitory activity
• ? -Pyrone

Cytospones E-J (1-6), six unreported alpha-pyrone derivatives, together with six known ones (7-12) were isolated from the solid culture of the endophytic fungus Cytospora rhizophorae A761, an endophytic fungus from Gynochthodes officinalis. The structures of the unreported compounds were unambiguously elucidated through spectroscopic analyses (1D, 2D NMR and HRESIMS), and their absolute configurations were assigned by single -crystal X-ray diffraction (Cu K alpha) analyses. Furthermore, cytospones E-J were evaluated for anti-inflammatory and alpha-glucosidase inhibitory activities.

• 单位
  中国科学院研究生院